Current Problems in Cancer
Volume 34, Issue 1 , Pages 38-46 , January 2010

Clinical Recognition, Diagnosis, and Staging of Merkel Cell Carcinoma, and the Role of the Multidisciplinary Management Team

  • Amod A. Sarnaik

      Affiliations

    • H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
    • ,
  • Mary H. Lien

      Affiliations

    • University of South Florida, Tampa, Forida
    • ,
  • Paul Nghiem

      Affiliations

    • University of Washington and Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Christopher K. Bichakjian

      Affiliations

    • University of Michigan, Ann Arbor, Michigan

References 

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  3. The Rockwell Merkel Cell Carcinoma Group. Merkel cell carcinoma: recent progress and current priorities on etiology, pathogenesis, and clinical management. J Clin Oncol. 2009;27:4021–4026
  4. Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF, et al. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol. 2008;58:375–381
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  6. Bobos M, Hytiroglou P, Kostopoulos I, Karkavelas G, Papadimitriou CS. Immunohistochemical distinction between Merkel cell carcinoma and small cell carcinoma of the lung. Am J Dermatopathol. 2006;28:99–104
  7. Merkel cell carcinoma.  Edge SB,  Byrd DR,  Carducci M, et al. editor. AJCC cancer staging manual. New York, NY: Springer; 2009;chap 30
  8. Lemos BD, Storer BE, Iyer JG, Phillips JL, Bichakjian CK, Fang LC, et al. Development of the first American joint committee on cancer staging system for Merkel cell carcinoma based upon prognostic factors analysis of 5,823 national cancer database cases. J Clin Oncol. 2009;(submitted for publication)
  9. Gupta SG, Wang LC, Peñas PF, Gellenthin M, Lee SJ, Nghiem P. Sentinel lymph node biopsy for evaluation and treatment of patients with Merkel cell carcinoma: the Dana-Farber experience and meta-analysis of the literature. Arch Dermatol. 2006;142:685–690
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  12. Meredith KL, Zager JS, Messina JL, Puleo CA, Cruse CW, Sondak VK. Management options for sentinel lymph node positive Merkel cell carcinoma. Ann Surg Oncol. 2007;14(suppl 2):29–30
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  14. Penn I, First MR. Merkel's cell carcinoma in organ recipients: report of 41 cases. Transplantation. 1999;68:1717–1721
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  16. Feng H, Shuda M, Chang Y, Moore PS. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008;319:1096–1100
  17. Merkel cell carcinoma Multicenter Interest Group (MMIG). http://merkelcell.org/MMIG.htmlAccessed October 1, 2009
  18. Iyer J, Koba S, Nghiem P. Toward better management of Merkel cell carcinoma using a consensus staging system, new diagnostic codes and a recently discovered virus. Actas Dermosifiliográficas. 2009;(submitted for publication)
  19. Miller SJ, Alam M, Andersen J, Berg D, Bichakjian CK, Bowen G, et al. Merkel cell carcinoma. J Natl Compr Canc Netw. 2006;4:704–712
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  23. The NCCN clinical practice guidelines in oncology™ Merkel cell carcinoma. [version 1.2009] http://www.nccn.org/professionals/physician_gls/f_guidelines.asp
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  25. Chen X, Siu LL. Impact of the media and the internet on oncology: survey of cancer patients and oncologists in Canada. J Clin Oncol. 2001;19:4291–4297
  26. Orringer JS, Fendrick AM, Trask PC, Bichakjian CK, Schwartz JL, Wang TS, et al. The effects of a professionally produced videotape on education and anxiety/distress levels for patients with newly diagnosed melanoma: a randomized, prospective clinical trial. J Am Acad Dermatol. 2005;53:224–229

PII: S0147-0272(10)00014-0

doi: 10.1016/j.currproblcancer.2010.01.002

Current Problems in Cancer
Volume 34, Issue 1 , Pages 38-46 , January 2010

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