Current Problems in Cancer
Volume 30, Issue 6 , Pages 298-306 , November 2006

Dealing with Multiple Endpoints

  • Amylou Dueck, PhD
    • ,
  • Paul J. Novotny, MS
    • ,
  • Jeff A. Sloan

      Affiliations

    • Corresponding Author InformationAddress correspondence to Dr. Jeff A. Sloan, Mayo Clinic, Section of Biostatistics, Department of Health Science Research, 200 First St. S.W., Rochester, MN 55905, USA

References 

  1. Loprinzi CL, Abu-Ghazaleh S, Sloan JA, van Haelst-Pisani C, Hammer AM, Rowland KM, et al. Phase III randomized double-blind study to evaluate the efficacy of a polycarbophil-based vaginal moisturizer in women with breast cancer. J Clin Oncol. 1997;15:969–973
  2. Rummans TA, Clark MM, Sloan JA, Frost MH, Bostwick JM, Atherton PJ, et al. Impacting quality of life for patients with advanced cancer with a structured multi-disciplinary intervention: a randomized controlled trial. J Clin Oncol. 2006;24:635–642
  3. Hahn EA, Glendenning GA, Sorensen MV, Hudgens SA, Druker BJ, Guilhot F, et al. Quality of life in patients with newly diagnosed chronic phase chronic myeloid leukemia on imatinib versus interferon alfa plus low-dose cytarabine: results from the IRIS Study. J Clin Oncol. 2003;21:2138–2146
  4. Bacik J, Mazumdar M, Murphy BA, Fairclough DL, Eremenco S, Mariani T, et al. The functional assessment of cancer therapy-BRM (FACT-BRM): a new tool for the assessment of quality of life in patients treated with biologic response modifiers. Qual Life Res. 2004;13:137–154
  5. Brooks R. EuroQol: the current state of play. Health Policy. 1996;37:53–72
  6. Loprinzi CL, Kugler JW, Sloan JA, Mailliard JA, LaVasseur BI, Barton DL, et al. Venlafaxine in management of hot flashes in survivors of breast cancer: a randomized controlled trial. Lancet. 2000;356:2059–2063
  7. Barton D, La Vasseur B, Loprinzi C, Novotny PJ, Wilwerding MB, Sloan JA. Venlafaxine for the control of hot flashes: results of a longitudinal continuation study. Oncol Nurs Forum. 2002;29:33–40
  8. Bender R, Lange S. Adjusting for multiple testing: when and how?. J Clin Epidemiol. 2001;54:343–349
  9. O’Brien PC. Procedures for comparing samples with multiple endpoints. Biometrics. 1984;40:1079–1087
  10. Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst. 2000;92:205–216
  11. Fairclough DL. Summary measures and statistics for comparison of quality of life in a clinical trial of cancer therapy. Stat Med. 1997;16:1197–1209
  12. Sloan JA, Loprinzi CL, Laurine JA, Novotny PJ, Vargas-Chanes D, Krook JE, et al. A simple stratification factor prognostic for survival in advanced cancer: the Good/Bad/Uncertain Index. J Clin Oncol. 2001;19:3539–3546
  13. Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994;23:129–138

PII: S0147-0272(06)00058-4

doi: 10.1016/j.currproblcancer.2006.08.007

Current Problems in Cancer
Volume 30, Issue 6 , Pages 298-306 , November 2006

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