Current Problems in Cancer
Volume 30, Issue 2 , Pages 40-98 , March 2006

The Role of Patients’ Response Expectancies in Side Effect Development and Control

References 

  1. Di Blasi Z , Crawford F , Bradley C , Kleijnen J , Klopfer B . Psychological variables in human cancer . J Project Tech . 1957;21:331–340 (cited in: Reactions to treatment debriefing among the participants of a placebo controlled trial. BMC Health Serv Res 2005;5:30)
  2. Cousins N . The Healing Heart (Antidotes to Panic and Helplessness) . New York, NY: W.W. Norton & Co; 1983;
  3. Kleijnen J , de Craen AJ , van Everdingen J , Krol L . Placebo effect in double-blind clinical trials (A review of interactions with medications) . Lancet . 1994;344:1347–1349
  4. Barsky AJ , Saintfort R , Rogers MP , Borus JF . Nonspecific medication side effects and the nocebo phenomenon . JAMA . 2002;287:622–627
  5. Evans RL , Smith KM , Halar EM , Kiolet CL . Effect of expectation and level of adjustment on treatment outcome . Psychol Rep . 1985;57:936–938
  6. Kaptchuk TJ . Powerful placebo (The dark side of the randomised controlled trial) . Lancet . 1998;351:1722–1725
  7. Kirsch I . Response expectancy as a determinant of experience and behavior . Am Psychol . 1985;40:1189–1202
  8. Levine JD , Gordon NC , Smith R , Fields HL . Analgesic responses to morphine and placebo in individuals with postoperative pain . Pain . 1981;10:379–389
  9. Peck C , Coleman G . Implications of placebo theory for clinical research and practice in pain management . Theoret Med . 1991;12:247–270
  10. Walach H , Jonas WB . Placebo research (The evidence base for harnessing self-healing capacities) . J Altern Complement Med . 2004;10(suppl 1):S103–S112
  11. Evans FJ . Expectancy, therapeutic instructions, and the placebo response . In:  White L ,  Tursky B ,  Schwartz GE editor. Placebo (Theory, Research and Mechanisms) . New York, NY: Guilford Press; 1985;p. 215–228
  12. Crow R , Gage H , Hampson S , Hart J , Kimber A , Thomas H . The role of expectancies in the placebo effect and their use in the delivery of health care (A systematic review) . Health Technol Assess . 1999;3:1–96
  13. Gidron Y , McGrath PJ , Goodday R . The physical and psychosocial predictors of adolescents’ recovery from oral surgery . J Behav Med . 1995;18:385–399
  14. Bachiocco V , Morselli AM , Carli G . Self-control expectancy and postsurgical pain (Relationships to previous pain, behavior in past pain, familial pain tolerance models, and personality) . J Pain Sympt Manage . 1993;8:205–214
  15. Scheier MF , Matthews KA , Owens JF , et al.   Dispositional optimism and recovery from coronary artery bypass surgery (The beneficial effects on physical and psychological well-being) . J Pers Soc Psychol . 1989;57:1024–1040
  16. Maeland JG , Havik OE . Psychological predictors for return to work after a myocardial infarction . J Psychosom Res . 1987;31:471–481
  17. Baker SL , Kirsch I . Cognitive mediators of pain perception and tolerance . J Pers Soc Psychol . 1991;61:504–510
  18. de Jong PJ , van Blast R , Arntz A , Merckelbach H . The placebo effect in pain reduction (The influence of conditioning experiences and response expectancies) . Int J Behav Med . 1996;3:14–29
  19. Montgomery GH . Mechanisms of placebo pain reduction (An empirical investigation) . Psychol Sci . 1996;7:174–176
  20. Price DD , Fields HL . The contribution of desire and expectation to placebo analgesia (Implications for new research strategies) . In:  Harrington A editors. The Placebo Effect (An Interdisciplinary Exploration) . Cambridge, MA: Harvard University Press; 1997;p. 117–137
  21. Disbrow EA , Bennett HL , Owings JT . Effect of preoperative suggestion on postoperative gastrointestinal motility . West J Med . 1993;158:488–492
  22. Voudouris NJ , Peck CL , Coleman G . Conditioned response models of placebo phenomena (Further support) . Pain . 1989;38:109–116
  23. Voudouris NJ , Peck CL , Coleman G . The role of conditioning and verbal expectancy in the placebo response . Pain . 1990;43:121–128
  24. Bennett HL , Benson MD , Kuiken DA . Preoperative instructions for decreased bleeding during spine surgery . Anesthesiology . 1986;65:A245
  25. Kiecolt-Glaser JK , Marucha PT , Atkinson C , Glaser R . Hypnosis as a modulator of cellular immune dysregulation during acute stress . J Consult Clin Psychol . 2001;69:674–682
  26. Smith GR , McDaniel SM . Psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans . Psychosom Med . 1983;45:65–70
  27. de la Fuente-Fernandez R , Ruth TJ , Sossi V , Schulzer M , Calne DB , Stoessl AJ . Expectation and dopamine release (Mechanism of the placebo effect in Parkinson’s disease) . Science . 2001;293:1164–1166
  28. Williams AR , Hind M , Sweeney BP , Fisher R . The incidence and severity of postoperative nausea and vomiting in patients exposed to positive intra-operative suggestions . Anaesthesia . 1994;49:340–342
  29. Benedetti F . How the doctor’s words affect the patient’s brain . Eval Health Prof . 2002;25:369–386
  30. Chvetzoff G , Tannock I . Placebo effects in oncology . J Natl Cancer Inst . 2003;95:19–29
  31. Di Blasi Z , Harkness E , Ernst E , Georgiou A , Kleijnen J . Influence of context effects on health outcomes (a systematic review) . Lancet . 2001;357:757–762
  32. Mondloch MV , Cole DC , Frank JW . Does how you do depend on how you think you’ll do? A systematic review of the evidence for a relation between patients’ recovery expectations and health outcomes . CMAJ (Canadian Medical Association Journal) . 2001;165:174–179
  33. Stewart-Williams S . The placebo puzzle (Putting together the pieces) . Health Psychol . 2004;23:198–206
  34. Forgione AG . Hypnosis in the treatment of dental fear and phobia . Dent Clin North Am . 1988;32:745–761
  35. Hahn RA . The nocebo phenomenon (concept, evidence, and implications for public health) . Prev Med . 1997;26:607–611
  36. Montgomery GH . Pre-infusion expectations predict post-treatment nausea during repeated adjuvant chemotherapy infusions for breast cancer . Br J Health Psychol . 2000;5:105–119
  37. Hofman M , Morrow GR , Roscoe JA , et al.   Cancer patients’ expectations of experiencing treatment-related side effects (A University of Rochester Cancer Center–Community Clinical Oncology Program study of 938 patients from community practices) . Cancer . 2004;101:851–857
  38. Barsky AJ , Saintfort R , Rogers MP , Borus JF , Khosla PP , Bajaj VK , et al.   Background noise in healthy volunteers (A consideration in adverse drug reaction studies) . Ind J Physiol Pharmacol . 1992;36:259–262 (cited in: Nonspecific medication side effects and the nocebo phenomenon. JAMA 2002;287:622-7)
  39. Nair MG , Hickok JT , Roscoe JA , Morrow GR . Sources of information used by patients to learn about chemotherapy side effects . J Cancer Educ . 2000;15:19–22
  40. Roscoe JA , Bushunow P , Morrow GR , et al.   Patient expectation is a strong predictor of severe nausea after chemotherapy (A University of Rochester Community Clinical Oncology Program study of patients with breast carcinoma) . Cancer . 2004;101:2701–2708
  41. Thorndyke PW , Hayes Roth B . The use of schemata in the acquisition and transfer of knowledge . Cognit Psychol . 1979;11:82–106
  42. Miller GA , Galanter E , Pribram KH . Plans and the structure of behavior . New York, NY: Holt, Rinehart & Winston; 1960;
  43. Neisser U . Cognition and reality . San Francisco, CA: Freeman; 1976;
  44. Rumelhart DE . Schemata and the cognitive system . In:  Wyer RS ,  Srull TK editor. Handbook of Social Cognition (Vol 1) . Hillsdale, NJ: Erlbaum; 1984;p. 161–186
  45. Broadbent DE . The hidden preattentive processes . Am Psychol . 1977;32:109–118
  46. White JD , Carlston DE . Consequences of schemata for attention, impressions, and recall in social interactions . J Pers Soc Psychol . 1983;45:538–549
  47. Blakeslee, S. Techniques to manage the mind: How hypnosis is gaining respect. Magazine for Hypnosis and Hypnotherapy. Available from: http://hypnos.co.uk/hypnomag/hypnosisnews/hypnosisrespect.htm
  48. Morris DB. Placebo, pain, and belief: A biocultural model. In: Harrington A, ed. The Placebo Effect: An Interdisciplinary Exploration. Cambridge, MA: Harvard University Press, 260:187-207.
  49. Meana M , Bunston T , George U , Wells L , Rosser W . Influences on breast cancer screening behaviors in Tamil immigrant women 50 years old and over . Ethn Health . 2001;6:179–188
  50. Shankar S , Figueroa-Valles N . Cancer knowledge and misconceptions (A survey of immigrant Salvadorean women) . Ethn Dis . 1999;9:201–211
  51. Peragallo NP , Fox PG , Alba ML . Breast care among Latino immigrant women in the U.S. . Health Care Women Int . 1998;19:165–172
  52. Miller AM , Champion VL . Attitudes about breast cancer and mammography (Racial, income, and educational differences) . Women Health . 1997;26:41–63
  53. Moodley R . Representation of subjective distress in black and ethnic minority patients (Constructing a research agenda) . Counselling Psychol Q . 2000;13:159–174
  54. Johnson JE . Self-regulation theory and coping with physical illness . Res Nurs Health . 1999;22:435–448
  55. Leventhal H , Nerenz DR , Steele DJ . Illness representations and coping with health threats . In:  Baum A ,  Taylor SE ,  Singer JE editor. Handbook of Psychology and Health (Social Psychological Aspects of Health (Vol IV)) . Hillsdale, NJ: Erlbaum; 1984;p. 219–252
  56. Leventahl H . Findings and theory in the study of fear communications . Adv Exp Soc Psychol . 1970;5:119–186
  57. Abramson LY , Seligman ME , Teasdale JD . Learned helplessness in humans (Critique and reformulation) . J Abnorm Psychol . 1978;87:49–74
  58. Rotter JB . Generalized expectancies for internal versus external control of reinforcement . Psychol Monogr . 1966;80:1–28
  59. Bandura A . Self-efficacy mechanism in human agency . Am Psychol . 1982;37:122–147
  60. Lazarus RS , Folkman S . Stress, appraisal, and coping . New York, NY: Springer; 1984;
  61. Scheier MF , Carver CS . Optimism, coping, and health (Assessment and implications of generalized outcome expectancies) . Health Psychol . 1985;4:219–247
  62. Scheier MF , Carver CS . Dispositional optimism and physical well-being (The influence of generalized outcome expectancies on health) . J Pers . 1987;55:169–210
  63. Scheier MF , Carver CS . Effects of optimism on psychological and physical well-being: Theoretical overview and empirical update. Special Issue: Cognitive perspectives in health psychology . Cognit Ther Res . 1992;16:201–228
  64. Hickok JT , Morrow GR , Roscoe JA , Pierce HI , Rosenbluth RJ . Prevalence and severity of acute and delayed NV associated with 3 highly emetogenic chemotherapies . Support Care Cancer, 13th International Symposium . 2001;9:289
  65. Hickok JT , Roscoe JA , Morrow GR , et al.   5-hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin (a URCC CCOP randomised controlled trial) . Lancet Oncology . 2005;6:765–772
  66. Roscoe JA , Morrow GR , Hickok JT , Stern RM . Nausea and vomiting remain a significant clinical problem (Trends over time in controlling chemotherapy-induced nausea and vomiting in 1413 patients treated in community clinical practices) . J Pain Symptom Manage . 2000;20:113–121
  67. Klastersky J , Schimpff SC , Senn HJ . Supportive Care in Cancer . New York, NY: Marcel Deckker; 1999;
  68. Osoba D , Zee B , Warr D , Latreille J , Kaizer L , Pater J . Effect of postchemotherapy nausea and vomiting on health-related quality of life. The Quality of Life and Symptom Control Committees of the National Cancer Institute of Canada Clinical Trials Group . Support Care Cancer . 1997;5:307–313
  69. Morrow GR . Chemotherapy-related nausea and vomiting (Etiology and management) . Can Cancer J Clin . 1989;39:89–104
  70. Gralla RJ , Itri LM , Pisko SE , et al.   Antiemetic efficacy of high-dose Metoclopramide (Randomized trials with placebo and Prochlorperazine in patients with chemotherapy-induced nausea and vomiting) . N Engl J Med . 1981;305:905–909
  71. Morrow GR , Roscoe JA , Hickok JT . Nausea and vomiting . In:  Holland JC editors. Psycho-Oncology . New York, NY: Oxford University Press; 1998;p. 476–484
  72. Rhodes VA , Watson PM , McDaniel RW , Hanson BM , Johnson MH . Expectation and occurrence of postchemotherapy side effects (Nausea and vomiting) . Cancer Pract . 1995;3:247–253
  73. Roscoe JA , Hickok JT , Morrow GR . Patient expectations as predictor of chemotherapy-induced nausea . Ann Behav Med . 2000;22:121–126
  74. Roscoe JA, Morrow GR, Bushunow P. Specific, and not generalized, response expectancies predict chemotherapy-induced nausea severity. Proceedings of the Society of Behavioral Medicine’s Twenty-Second Annual Meeting 23:S074, 2001.
  75. Roscoe JA , Morrow GR , Hickok JT , et al.   Expectations of nausea, but not trait optimism, predict chemotherapy-induced nausea severity . Support Care Cancer, 13th International Symposium . 2001;9:291
  76. Jacobsen PB , Andrykowski MA , Redd WH , et al.   Nonpharmacologic factors in the development of posttreatment nausea with adjuvant chemotherapy for breast cancer . Cancer . 1988;61:379–385
  77. Haut MW , Beckwith B , Laurie JA , Klatt N . Postchemotherapy nausea and vomiting in cancer patients receiving outpatient chemotherapy . J Psychosoc Oncol . 1991;9:117–130
  78. Stein KD , Jacobsen PB . Expectancies, perceived control, and severity of physical side effects of adjuvant chemotherapy for breast cancer . Psychosom Med . 1998;60:121
  79. Olver IN , Taylor AE , Whitford HS . Relationships between patients’ pre-treatment expectations of toxicities and post chemotherapy experiences . Psychooncology . 2005;14:25–33
  80. Montgomery GH , Bovbjerg DH . Expectations of chemotherapy-related nausea (emotional and experiential predictors) . Ann Behav Med . 2003;25:48–54
  81. Andrykowski MA , Redd WH , Hatfield AK . Development of anticipatory nausea (a prospective analysis) . J Consult Clin Psychol . 1985;53:447–454
  82. Watson M , McCarron J , Law M . Anticipatory nausea and emesis, and psychological morbidity (Assessment of prevalence among out-patients on mild to moderate chemotherapy regimens) . Br J Cancer . 1992;66:862–866
  83. Zook DJ , Yasko JM . Psychologic factors (Their effect on nausea and vomiting experienced by clients receiving chemotherapy) . Oncol Nurs Forum . 1983;10:76–81
  84. Cassileth BR , Lusk EJ , Bodenheimer BJ , Farber JM , Jochimsen P , Morrin-Taylor B . Chemotherapeutic toxicity–the relationship between patients’ pretreatment expectations and posttreatment results . Am J Clin Oncol . 1985;8:419–425
  85. Andrykowski MA , Gregg ME . The role of psychological variables in post-chemotherapy nausea (Anxiety and expectation) . Psychosom Med . 1992;54:48–58
  86. Wickham R . Managing chemotherapy-related nausea and vomiting (The state of the art) . Oncol Nurs Forum . 1989;16:563–574
  87. Roscoe JA , Morrow GR , Hickok JT , Mustian KM , Shelke AR . Biobehavioral factors in chemotherapy induced nausea and vomiting . J Natl Comprehens Cancer Network . 2005;2:501–508
  88. al Absi M , Rokke PD . Can anxiety help us tolerate pain? . Pain . 1991;46:43–51
  89. Cornwall A , Donderi DC . The effect of experimentally induced anxiety on the experience of pressure pain . Pain . 1988;35:105–113
  90. Spiegel D , Bloom JR . Pain in metastatic breast cancer . Cancer . 1983;52:341–345
  91. Jensen MP , Turner JA , Romano JM . Self-efficacy and outcome expectancies (Relationship to chronic pain coping strategies and adjustment) . Pain . 1991;44:263–269
  92. Litt MD . Self-efficacy and perceived control (Cognitive mediators of pain tolerance) . J Pers Soc Psychol . 1988;54:149–160
  93. O’Leary A . Self-efficacy and health . Behav Res Health . 1985;23:437–451
  94. Reese LB . Coping with pain (The role of perceived self-efficacy (Doctoral dissertation, Stanford University)) . Dissert Abstr Int . 1983;212: AAC-8320627
  95. Gattuso SM , Litt MD , Fitzgerald TE . Coping with gastrointestinal endoscopy (Self-efficacy enhancement and coping style) . J Consult Clin Psychol . 1992;60:133–139
  96. Holroyd KA . Change mechanisms in EMG biofeedback training (Cognitive changes underlying improvements in tension headache) . J Consult Clin Psychol . 1984;52:1039–1053
  97. Turk DC , Feldman CS . Noninvasive approaches to pain control in terminal illness (The contribution of psychological variables) . Hosp J . 1992;8:1–23
  98. Johnson JE . Effects of accurate expectations about sensations on the sensory and distress components of pain . J Pers Soc Psychol . 1973;27:261–275
  99. Ahles TA , Martin JB . Cancer pain (A multidimensional perspective) . Hosp J . 1992;8:25–48
  100. Main CJ , Spanswick CC . Pain (Psychological and psychiatric factors) . Br Med Bull . 1991;47:732–742
  101. Rudy TE , Turk DC . Psychological aspects of pain . Int Anesthesiol Clin . 1991;29:9–21
  102. Amanzio M , Benedetti F . Neuropharmacological dissection of placebo analgesia (expectation-activated opioid systems versus conditioning-activated specific subsystems) . J Neurosci . 1999;19:484–494
  103. Montgomery GH , Bovbjerg DH . Presurgery distress and specific response expectancies predict postsurgery outcomes in surgery patients confronting breast cancer . Health Psychology . 2004;23(4):381–387
  104. Pollo A , Amanzio M , Arslanian A , Casadio C , Maggi G , Benedetti F . Response expectancies in placebo analgesia and their clinical relevance . Pain . 2001;93:77–84
  105. Wallace LM . Surgical patients’ expectations of pain and discomfort (does accuracy of expectations minimise post-surgical pain and distress?) . Pain . 1985;22:363–373
  106. Price DD , Milling LS , Kirsch I , Duff A , Montgomery GH , Nicholls SS . An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm . Pain . 1999;83:147–156
  107. Vase L , Robinson ME , Verne GN , Price DD . Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms . Pain . 2005;115:338–347
  108. Montgomery GH , Kirsch I . Classical conditioning and the placebo effect . Pain . 1997;72:107–113
  109. Amanzio M , Pollo A , Maggi G , Benedetti F . Response variability to analgesics (a role for non-specific activation of endogenous opioids) . Pain . 2001;90:205–215
  110. Beecher HK . The powerful placebo . JAMA . 1955;159:1602–1606
  111. Miller NE . Placebo factors in treatment (Views of a psychologist) . In:  Shepherd M ,  Sartorius N editor. Non-Specific Aspects of Treatment . Toronto: Hans Huber; 1989;p. 39–51
  112. Wall PD . Pain and the placebo response . Ciba Found Symp . 1993;174:187–211
  113. Rose DA , Kahan TL . Melatonin and sleep qualities in healthy adults (Pharmacological and expectancy effects) . J Gen Psychol . 2001;128:401–421
  114. Hofman M, Jean-Pierre P, Roscoe JA, Morrow GR. Relationship of patients’ expectations and occurrence of cancer treatment side effects: A University of Rochester Cancer Center Community Clinical Oncology Program study. University of Rochester James P Wilmot Cancer Center 10th Annual Scientific Symposium 2005.
  115. Eden D , Zuk Y . Seasickness as a self-fulfilling prophecy (Raising self-efficacy to boost performance at sea) . J Appl Psychol . 1995;80:628–635
  116. Wolf S . Effects of suggestion and conditioning on the action of chemical agents in human subjects (The pharmacology of placebos) . J Clin Invest . 1950;29:100–109
  117. Lauder GR , McQuillan PJ , Pickering RM . Psychological adjunct to perioperative antiemesis . Br J Anaesth . 1995;74:266–270
  118. Booth RJ , Petrie KJ , Brook RJ . Conditioning allergic skin responses in humans (A controlled trial) . Psychosom Med . 1995;57:492–495
  119. Völgyesi FA . “School for patients”, hypnosis-therapy and psycho-prophylaxis . Br J Med Hypn . 1954;5:8–17
  120. Kienle GS , Kiene H . Placebo effect and placebo concept (A critical methodological and conceptual analysis of reports on the magnitude of the placebo effect) . Altern Ther Health Med . 1996;2:39–54
  121. Morrow GR, Roscoe JA, Hickok JT, et al. A modest response expectancy manipulation changes expectations for the development of chemotherapy-induced nausea but fails to reduce nausea severity. University of Rochester James P Wilmot Cancer Center 6th Annual Scientific Symposium, 2001.
  122. Kirsch I . How Expectancies Shape Experience . Washington, DC: American Psychological Association; 1999;
  123. Krassner AM . Hypnotherapy . In:  Strohecker J editors. Alternative Medicine (The Definitive Guide) . Fife, WA: Future Medicine Publishing; 1994;p. 306–312
  124. Kirsch I . Hypnosis and placebos (Response expectancy as a mediator of suggestion effects) . Anales de Psicologia . 1999;15:99–110
  125. Kirsch I . Clinical hypnosis as a nondeceptive placebo. Dissociation, Trauma, Memory, and Hypnosis Book Series . In:  Kirsch I ,  Capafons A , et al. editor. Clinical Hypnosis and Self-Regulation (Cognitive-Behavioral Perspectives) . Washington, DC: American Psychological Association; 1999;p. 211–225
  126. Kirsch I . The response set theory of hypnosis . Am J Clin Hypn . 2000;42:274–292
  127. Benham G , Bowers S , Nash M , Muenchen R . Self-fulfilling prophecy and hypnotic response are not the same thing . J Pers Soc Psychol . 1998;75(6):1604–1613
  128. Gandhi B , Oakley DA . Does ‘hypnosis’ by any other name smell as sweet? The efficacy of ‘hypnotic’ inductions depends on the label ‘hypnosis.’ . Consciousness Cognition . 2005;14(2):304–315
  129. Zeltzer L , Kellerman J , Ellenberg L , Dash J . Hypnosis for reduction of vomiting associated with chemotherapy and disease in adolescents with cancer . J Adolesc Health Care . 1983;4:77–84
  130. Kellerman J , Zeltzer L , Ellenberg L , Dash J . Adolescents with cancer. Hypnosis for the reduction of the acute pain and anxiety associated with medical procedures . J Adolesc Health Care . 1983;4(2):85–90
  131. Marchioro G , Azzarello G , Viviani F , et al.   Hypnosis in the treatment of anticipatory nausea and vomiting in patients receiving cancer chemotherapy . Oncology . 2000;59(2):100–104
  132. Stalpers LJ , da Costa HC , Merbis MA , Fortuin AA , Muller MJ , van Dam FS . Hypnotherapy in radiotherapy patients (a randomized trial) . Int J Radiat Oncol Biol Physics . 2005;61(2):499–506
  133. Bakke AC , Purtzer MZ , Newton P . The effect of hypnotic-guided imagery on psychological well-being and immune function in patients with prior breast cancer . J Psychosomat Res . 2002;53(6):1131–1137
  134. DuHamel KN , Redd WH , Vickberg SM . Behavioral interventions in the diagnosis, treatment and rehabilitation of children with cancer. [Review] . Acta Oncol . 1999;38(6):719–734
  135. Liossi C , Hatira P . Clinical hypnosis versus cognitive behavioral training for pain management with pediatric cancer patients undergoing bone marrow aspirations . Int J Clin Exp Hypnosis . 1999;47(2):104–116
  136. Rapkin DA , Straubing M , Holroyd JC . Guided imagery, hypnosis and recovery from head and neck cancer surgery (an exploratory study) . Int J Clin Exp Hypnosis . 1991;39(4):215–226
  137. Elkins G , Marcus J , Palamara L , Stearns V . Can hypnosis reduce hot flashes in breast cancer survivors? A literature review. [Review] . Am J Clin Hypnosis . 2004;47(1):29–42
  138. Lang EV , Rosen MP . Cost analysis of adjunct hypnosis with sedation during outpatient interventional radiologic procedures . Radiology . 2002;222(2):375–382
  139. Spira JL , Spiegel D . Hypnosis and related techniques in pain management . Hosp J . 1992;8:89–119
  140. Zeltzer L , LeBaron S . Hypnosis and nonhypnotic techniques for reduction of pain and anxiety during painful procedures in children and adolescents with cancer . J Pediatr . 1982;101:1032–1035
  141. Bonilla KB , Quigley WF , Bowers WF . Experiences with hypnosis on a surgical service . Mil Med . 1961;126:364–370
  142. Malone MD , Kurtz RM , Strube MJ . The effects of hypnotic suggestion on pain report . Am J Clin Hypn . 1989;31:221–230
  143. Hilgard ER , Macdonald H , Morgan AH , Johnson LS . The reality of hypnotic analgesia (A comparison of highly hypnotizables with simulators) . J Abnorm Psychol . 1978;87:239–246
  144. Calvert EL , Houghton LA , Cooper P , Morris J , Whorwell PJ . Long-term improvement in functional dyspepsia using hypnotherapy . Gastroenterology . 2002;123(6):1778–1785
  145. Giorlando S , Mascola R . The treatment of hyperemesis gravidarum with hypnotherapy . Am J Obstet Gynecol . 1957;73:444–447
  146. Kroger W , DeLee S . The psychosomatic treatment of hyperemesis gravidarum by hypnosis . Am J Obstet Gynecol . 1946;51:544–552
  147. Colgan SM , Faragher EB , Whorwell PJ . Controlled trial of hypnotherapy in relapse prevention of duodenal ulceration . Lancet . 1988;1(8598):1299–1300
  148. Ewer TC , Stewart DE . Improvement in bronchial hyper-responsiveness in patients with moderate asthma after treatment with a hypnotic technique (a randomised controlled trial) . Br Med J Clin Res Ed . 1986;293(6555):1129–1132
  149. Ginandes C , Brooks P , Sando W , Jones C , Aker J . Can medical hypnosis accelerate post-surgical wound healing? Results of a clinical trial . Am J Clin Hypnosis . 2003;45(4):333–351
  150. Ikemi Y , Nakagawa S . A psychosomatic study of contagious dermatitis . Kyushu J Med Sci . 1962;13:335–350
  151. Ewin DM . Hypnotherapy for warts (verruca vulgaris) (41 consecutive cases with 33 cures) . Am J Clin Hypn . 1992;35:1–10
  152. Thomson L . A project to change the attitudes, beliefs and practices of health professionals concerning hypnosis . Am J Clin Hypnosis . 2003;46(1):31–44
  153. Lang EV , Berbaum KS . Educating interventional radiology personnel in nonpharmacologic analgesia (effect on patients’ pain perception) . Acad Radiol . 1997;4(11):753–757
  154. Carey MP , Burish TG . Etiology and treatment of the psychological side effects associated with cancer chemotherapy (A critical review and discussion) . Psychol Bull . 1988;104:307–325
  155. Martinez-Tendero J , Capafons A , Weber V , Cardena E . Rapid self-hypnosis (a new self-hypnosis method and its comparison with the Hypnotic Induction Profile (HIP)) . Am J Clin Hypnosis . 2001;44(1):3–11
  156. Deng G , Cassileth BR . Integrative oncology (complementary therapies for pain, anxiety, and mood disturbance) . [Review] Can Cancer J Clinicians . 2005;55(2):109–116
  157. Wootton JC , Sparber A . Surveys of complementary and alternative medicine: part I. General trends and demographic groups . [Review] J Altern Complement Med . 2001;7:195–208
  158. Patterson RE , Neuhouser ML , Hedderson MM , et al.   Types of alternative medicine used by patients with breast, colon, or prostate cancer (predictors, motives, and costs) . J Altern Complement Med . 2002;8:477–485
  159. Yates JS , Mustian KM , Morrow GR , et al.   Prevalence of complimentary and alternative medicine use in cancer patients during adjuvant therapy . Support Care Cancer . 2005;13:806–811
  160. What is Complementary and Alternative Medicine (CAM)? National Center for Complementary and Alternative Medicine, NCCAM Publication No. D156. May 2002.
  161. Ernst E , Resch KL , White AR . Complementary medicine. What physicians think of it: a meta-analysis . Arch Intern Med . 1995;155:2405–2408
  162. Kaptchuk TJ , Berman BM , Bausell RB . The placebo and complementary and alternative medicine: historical, scientific and methodological considerations. Expert Panels in Cancer CAM Research: Developing the State of the Science in Research Methodologies . In: The NCI’s Office of Cancer and Alternative Medicine . Washington DC: National Cancer Institute; 2003;p. 29–45
  163. Astin JA , Marie A , Pelletier KR , Hansen E , Haskell WL . A review of the incorporation of complementary and alternative medicine by mainstream physicians . Arch Intern Med . 1998;158:2303–2310
  164. Brown E . Complementary and alternative medicine. The daunting challenge . Physician Exec . 1998;24(6):16–21
  165. Frank JD . Biofeedback and the placebo effect . Biofeedback Self Regul . 1982;7:449–460
  166. Joyce CRB . Placebo and complementary medicine . Lancet . 1994;344:1279–1281
  167. Lynoe N . Is the effect of alternative medical treatment only a placebo effect? . Scand J Soc Med . 1999;18:149–153
  168. Koretz RL , Rotblatt M . Complementary and alternative medicine in gastroenterology (The good, the bad, and the ugly) . Clin Gastroenterol Hepatol . 2004;2:957–967
  169. Peters D . Understanding the Placebo Effect in Complementary Medicine . London: Harcourt; 2001;
  170. Relman A . A critical view . Adv Mind Body Med . 2001;17:68–70
  171. Kirsch I . Changing Expectations (A Key to Effective Psychotherapy) . Pacific Grove, CA: Brooks/Cole; 1990;
  172. Berman BM , Bausell RB . The use of non-pharmacological therapies by pain specialists . Pain . 2000;85:313–315
  173. Ezzo J , Vickers A , Richardson MA , et al.   Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting . J Clin Oncol . 2005;23:7188–7198
  174. Villaire M . NIH consensus conference confirms acupuncture’s efficacy . Altern Ther Health Med . 1998;4:21–30
  175. Bausell RB , Lao L , Bergman S , Lee WL , Berman BM . Is acupuncture analgesia an expectancy effect? Preliminary evidence based on participants’ perceived assignments in two placebo-controlled trials . Eval Health Prof . 2005;28:9–26
  176. Pariente J , White P , Frackowiak RSJ , Lewith G . Expectancy and belief modulate the neuronal substrtes of pain treated by acupuncture . NeuroImage . 2005;25:1161–1167
  177. Ferrara-Love R , Sekeres L , Bircher NG . Nonpharmacologic treatment of postoperative nausea . J Perianesth Nurs . 1996;11:378–383
  178. Alkaissi A , Stalnert M , Kalman S . Effect and placebo effect of acupressure (P6) on nausea and vomiting after outpatient gynaecological surgery . Acta Anaesthesiol Scand . 1999;43:270–274
  179. Roscoe JA , Morrow GR , Hickok JT , et al.   The efficacy of acupressure and acustimulation wrist bands for the relief of chemotherapy-induced nausea and vomiting (A URCC CCOP multicenter study) . J Pain Symptom Manage . 2003;26:731–742
  180. Kalauokalani D , Cherkin DC , Sherman KJ , Koepsell TD , Deyo RA . Lessons from a trial of acupuncture and massage for low back pain (patient expectations and treatment effects) . Spine . 2001;26:1418–1424
  181. So DW . Acupuncture outcomes, expectations, patient-provider relationship, and the placebo effect (implications for health promotion) . Am J Public Health . 2002;92:1662–1667
  182. Morrow GR , Roscoe JA . Anticipatory nausea and vomiting (Models, mechanisms and management) . In:  Dicato M editors. Medical Management of Cancer Treatment Induced Emesis . London: Martin Dunitz; 1997;p. 149–166
  183. Morrow GR , Roscoe JA , Hynes HE , Flynn PJ , Pierce HI , Burish T . Progress in reducing anticipatory nausea and vomiting (A study of community practice) . Support Care Cancer . 1998;6:46–50
  184. Hickok JT , Roscoe JA , Morrow GR . The role of patients’ expectations in the development of anticipatory nausea related to chemotherapy for cancer . J Pain Symptom Manage . 2001;22:843–850
  185. Morrow GR , Roscoe JA , Kirshner JJ , Hynes HE , Rosenbluth RJ . Anticipatory nausea and vomiting in the era of 5-HT3 antiemetics . Support Care Cancer . 1998;6:244–247
  186. Challis GB , Stam HJ . A longitudinal study of the development of anticipatory nausea and vomiting in cancer chemotherapy patients (the role of absorption and autonomic perception) . Health Psychology . 1992;11(3):181–189
  187. Tyc VL , Mulhern RK , Bieberich AA . Anticipatory nausea and vomiting in pediatric cancer patients (an analysis of conditioning and coping variables) . J Dev Behav Pediatr . 1997;18(1):27–33
  188. Dolgin MJ , Katz ER , McGinty K , Siegel SE . Anticipatory nausea and vomiting in pediatric cancer patients . Pediatrics . 1985;75:547–552
  189. Andrykowski MA , Jacobsen PB , Marks E , et al.   Prevalence, predictors, and course of anticipatory nausea in women receiving adjuvant chemotherapy for breast cancer . Cancer . 1988;62:2607–2613
  190. Andrykowski MA . The role of anxiety in the development of anticipatory nausea in cancer chemotherapy (A review and synthesis) . Psychosom Med . 1990;52:458–475
  191. Watson M . Anticipatory nausea and vomiting (broadening the scope of psychological treatments) . Support Care Cancer . 1993;1:171–177
  192. Montgomery GH , Tomoyasu N , Bovbjerg DH , et al.   Patients’ pretreatment expectations of chemotherapy-related nausea are an independent predictor of anticipatory nausea . Ann Behav Med . 1998;20:104–109
  193. Paul GL . Insight versus desensitization in psychotherapy two years after termination . J Consult Clin Psychol . 1966;31:333–348
  194. Kirsch I . Specifying nonspecifics (Psychological mechanisms of placebo effects) . In:  Harrington A editors. The Placebo Effect (An Interdisciplinary Exploration) . Cambridge, MA: Harvard University Press; 1997;p. 166–186
  195. Rescorla RA . Pavlovian conditioning (It’s not what you think) . Am Psychol . 1988;43:151–160
  196. Stewart-Williams S , Podd J . The placebo effect (Dissolving the expectancy versus conditioning debate) . Psychol Bull . 2004;130:324–340
  197. Kirsch I , Lynn SJ , Vigorito M , Miller RR . The role of cognition in classical and operant conditioning . J Clin Psychol . 2004;60(4):369–392
  198. Watson M , Meyer L , Thomson A , Osofsky S . Psychological factors predicting nausea and vomiting in breast cancer patients on chemotherapy . Eur J Cancer . 1998;34:831–837
  199. Montgomery GH , Bovbjerg DH . Specific response expectancies predict anticipatory nausea during chemotherapy for breast cancer . J Consult Clin Psychol . 2001;69(5):831–835
  200. Taylor SE , Brown JD . Illusion and well-being (A social psychological perspective on mental health) . Psychol Bull . 1988;103:193–210
  201. Carver CS , Gaines JG . Optimism, pessimism, and postpartum depression . Cogn Ther Res . 1987;11:449–462
  202. Fitzgerald TE , Tennen H , Affleck G , Pransky GS . The relative importance of dispositional optimism and control appraisals in quality of life after coronary artery bypass surgery . J Behav Med . 1993;16:25–43
  203. Carver CS , Pozo C , Harris SD , et al.   How coping mediates the effect of optimism on distress (A study of women with early stage breast cancer) . J Pers Soc Psychol . 1993;65:375–390
  204. Johnson JE . Coping with radiation therapy (Optimism and the effect of preparatory interventions) . Res Nurs Health . 1996;19:3–12
  205. Greer S . Psychological response to cancer and survival . Psychol Med . 1991;21:43–49
  206. Peterson C , Seligman ME , Vaillant GE . Pessimistic explanatory style is a risk factor for physical illness (A thirty-five-year longitudinal study) . J Pers Soc Psychol . 1988;55:23–27
  207. Solomon GF , Temoshok L , O’Leary A , Zich J . An intensive psychoimmunologic study of long-surviving persons with AIDS (Pilot work, background studies, hypotheses, and methods) . Ann N Y Acad Sci . 1987;496:647–655
  208. King KB , Rowe MA , Kimble LP , Zerwic JJ . Optimism, coping and long-term recovery from coronary artery surgery in women . Res Nurs Health . 1998;21:15–26
  209. Chamberlain K , Petrie K , Azariah R . The role of optimism and sense of coherence in predicting recovery following surgery . Psychol Health . 1992;7:301–310
  210. Segerstrom SC , Taylor SE , Kemeny ME , Fahey JL . Optimism is associated with mood, coping and immune change in response to stress . J Pers Soc Psychol . 1998;74:1646–1655
  211. Kamen-Siegel L , Rodin J , Seligman MEP , Dwyer J . Explanatory style and cell-mediated immunity in elderly men and women . Health Psychol . 1991;10:229–235
  212. Scheier MF , Carver CS , Bridges MW . Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem) (A reevaluation of the Life Orientation Test) . J Pers Soc Psychol . 1994;67:1063–1078
  213. Roscoe JA, Morrow GR, Hickok JT, Pierce HI, Flynn PJ, Dakhil SR. Patient characteristics associated with the development of chemotherapy-induced nausea. Support Care Cancer, 14th International Symposium 2002;10:363.
  214. Shapiro AK , Morris LA . The placebo effect in medical and psychological therapies . In:  Garfield SL ,  Bergin AE editor. Handbook of Psychotherapy and Behavior Change . New York, NY: John Wiley & Sons; 1978;p. 369–410
  215. Wickramasekera I . A conditioned response model of the placebo effect (Predictions from the model) . In:  White L ,  Tursky B ,  Schwartz GE editor. Placebo (Theory, Research and Mechanisms) . New York, NY: Guilford Press; 1985;p. 255–287
  216. Moore ME , Berk SN . Acupuncture for chronic shoulder pain. An experimental study with attention to the role of placebo and hypnotic susceptibility . Ann Intern Med . 1976;84:381–384
  217. Grunbaum A . Explications and implications of the placebo concept . In:  White L ,  Tursky B ,  Schwartz GE editor. Placebo (Theory, Research and Mechanisms) . New York, NY: Guilford Press; 1985;p. 9–36
  218. Buckalew LW , Ross S , Starr BJ . Nonspecific factors in drug effects (Placebo personality) . Psychol Rep . 1981;48:3–8
  219. Shapiro AK . The Powerful Placebo (From Ancient Priest to Modern Physician) . Baltimore, MD: Johns Hopkins University Press; 1997;
  220. Gallimore RG , Turner JL . Contempory studies of placebo phenomena . In:  Jarvik ME editors. Psychopharmacology in the Practice of Medicine . New York, NY: Appleton-Century-Crofts; 1977;
  221. Froehlich JC . Opioid peptides . Neurotransmitter Rev . 1997;21:132–136
  222. Bodnar RJ , Klein GE . Endogenous opiates and behavior (2004 Peptides) . Peptides . 2005;26:2629–2711
  223. Reznikov AG , Nosenko ND , Tarasenko LV . Opioids are responsible for neurochemical feminization of the brain in prenatally stressed male rats . Neuroendocrinol Lett . 2005;26:35–38
  224. Levine JD , Gordon NC , Fields HL . The mechanism of placebo analgesia . Lancet . 1978;2:654–657
  225. Definition of Naloxone. Medicine Net.Com. August 7 2004.
  226. Benedetti F , Amanzio M , Maggi G . Potentiation of placebo analgesia by proglumide . Lancet . 1995;346:1231
  227. Benedetti F , Amanzio M . The neurobiology of placebo analgesia (from endogenous opioids to cholecystokinin) . Prog Neurobiol . 1997;52:109–125
  228. Fields HL , Levine JD . Placebo analgesia (a role for endorphins?) . Trends Neurosci . 1984;7:271–273
  229. Grevert P , Albert LH , Goldstien A . Partial antagonism of placebo analgesia by naloxone . Pain . 1983;16:129–143
  230. Levine JD , Gordon NC . Influence of the method of drug administration on analgesic response . Nature . 1984;312:755–756
  231. Levine JD , Gordon NC . Method of administration determines the effect of naloxone on pain . Brain Res . 1986;365:377–378
  232. Benedetti F , Amanzio M , Baldi S , Casadio C , Maggi G . Inducing placebo respiratory depressant responses in humans via opioid receptors . Eur J Neurosci . 1999;11:625–631
  233. Holden C . Neuroscience. Drugs and placebos look alike in the brain . Science . 2002;295:947
  234. Petrovic P , Dietrich T , Fransson P , Andersson J , Carlsson K , Ingvar M . Placebo in emotional processing–induced expectations of anxiety relief activate a generalized modulatory network . Neuron . 2005;46:957–969
  235. Mayberg HS , Silva JA , Brannan SK , et al.   The functional neuroanatomy of the placebo effect . Am J Psychiatry . 2002;159(5):728–737
  236. Wager TD , Rilling JK , Smith EE , et al.   Placebo-induced changes in FMRI in the anticipation and experience of pain . Science . 2004;303:1162–1167
  237. Turner JA , Deyo RA , Loeser JD , Von Korff M , Fordyce WE . The importance of placebo effects in pain treatment and research . JAMA . 1994;271:1609–1614
  238. Dossey L . How should alternative therapies be evaluated? An examination of fundamentals . Altern Ther Health Med . 1995;1:6–10
  239. Feinstein AR . Current problems and future challenges in randomized clinical trials . Circulation . 1984;70:767–774
  240. Allan LG , Siegel S . A signal detection theory analysis of the placebo effect . Eval Health Prof . 2002;25:410–420
  241. Morrow GR , Hickok JT , Roscoe JA , Matteson SE . Theory, hypothesis development, and randomized clinical trials in complementary and alternative medicine (A beginning at separating science from political science) . In: Expert Opinions on Methodology: Development of Cancer CAM Symptom Research. Publication Number 03-5427 . Bethesda, MD: NCI; 2003;p. 91–104
  242. Ewin DM . The use of hypnosis in the treatment of burn patients . Psychiatr Med . 1992;10:79–87
  243. Enqvist B , Bjorklund C , Engman M , Jakobsson J . Preoperative hypnosis reduces postoperative vomiting after surgery of the breasts. A prospective, randomized and blinded study . Acta Anaesthesiol Scand . 1997;41:1028–1032
  244. Enqvist B , von Konow L , Bystedt H . Pre- and perioperative suggestion in maxillofacial surgery (Effects on blood loss and recovery) . Int J Clin Exp Hypn . 1995;43:284–294
  245. Eberhart LH , Doring HJ , Holzrichter P , Roscher R , Seeling W . Therapeutic suggestions given during neurolept-anaesthesia decrease post-operative nausea and vomiting . Eur J Anaesthesiol . 1998;15:446–452
  246. Benedetti F , Arduino C , Amanzio M . Somatotopic activation of opioid systems by target-directed expectations of analgesia . J Neurosci . 1999;19:3639–3648
  247. Lebovits AH , Twersky R , McEwan B . Intraoperative therapeutic suggestions in day-case surgery (are there benefits for postoperative outcome? [see comment]) . Br J Anaesth . 1999;82:861–866
  248. De Pascalis V , Chiaradia C , Carpenter DO . The contribution of suggestibility and expectation to placebo analgesia phenomenon in an experimental setting . Pain . 2002;96:393–402

 Supported by Grant U10CA 37420 from the National Cancer Institute and Grant RSG 01071-010PBP from the American Cancer Society.

PII: S0147-0272(05)00089-9

doi: 10.1016/j.currproblcancer.2005.12.001

Current Problems in Cancer
Volume 30, Issue 2 , Pages 40-98 , March 2006

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