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Current Problems in Cancer
Volume 30, Issue 1
, Pages 7-32
, January 2006
Targeting VEGF in Cancer Therapy
References
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AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases
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Phase I study of AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases
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Phase I trial of anti-sense oligonucleotide vascular endothelial growth factor (VEGF-AS, Veglin) in patients with relapsed and refractory malignancies
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Multitargeted kinase inhibitors in non-small-cell lung cancer
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Irinotecan (I), carboplatin (C), and radiotherapy (RT) followed by bevacizumab (B) in the treatment of limited-stage small cell lung cancer (SCLC)
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ZD6474, a novel antiangiogenic agent, in combination with docetaxel in patients with NSCLC
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A randomized, placebo-controlled phase II trial of ZD6474 plus docetaxel in patients with NSCLC
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Phase I trial of oral CP-547,632 (VEGFR2) in combination with paclitaxel (P) and carboplatin (C) in advanced non-small cell lung cancer (NSCLC)
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Phase II trial of the anti-VEGF antibody bevacizumab in combination with vinorelbine for refractory advanced breast cancer
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CTEP-sponsored phase II trial of bevacizumab (Avastin®) in combination with docetaxel (Taxotere) in metastatic breast cancer
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Phase I combined biological therapy of breast cancer using two humanized monoclonal antibodies directed against HER2 proto-oncogene and vascular endothelial growth factor (VEGF)
.
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. 2004;88:S124
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Phase II trial of erlotonib (OSI-774), an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, and bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF), in patients (pts) with metastatic breast cancer (MBC)
.
Proc Am Soc Clin Oncol
. 2004;2001a
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A feasibility study of an aromatase inhibitor (AI), letrozole (L), and the antibody to vascular endothelial growth factor (VEGF), bevacizumab (B), in patients with hormone receptor-positive metastatic breast cancer (MBC)
.
Proc Am Soc Clin Oncol
. 2005;796a
-
Phase II trial of neoadjuvant docetaxel with or without bevacizumab in patients with locally advanced breast cancer
.
Breast Cancer Res Treat
. 2004;88:S106
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A pilot study to evaluate response and angiogenesis after treatment with bevacizumab in patients with inflammatory breast cancer
.
Proc Am Soc Clin Oncol
. 2004;578a
-
Phase III trial of capecitabine (Xeloda) plus bevacizumab (Avastin) versus capecitabine alone in women with metastatic breast cancer (MBC) previously treated with an anthracycline and a taxane
.
Breast Cancer Res Treat
. 2002;76:S37
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The role of VEGF expression in response to bevacizumab plus capecitabine in metastatic breast cancer (MBC)
.
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- A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer . Clin Cancer Res . 2005;11:3369–3376
PII: S0147-0272(05)00088-7
doi: 10.1016/j.currproblcancer.2005.11.001
© 2006 Elsevier Inc. All rights reserved.
« Previous
Current Problems in Cancer
Volume 30, Issue 1
, Pages 7-32
, January 2006
