Ross A. Abrams, MD, is the Director of Radiation Oncology and Associate Professor of Oncology at the Sidney Kimmel Cancer Center at Johns Hopkins. Dr Abrams has been actively involved in the clinical management and research of pancreatic cancer since 1991 and has been actively involved in the development of clinical trials involving chemoradiation therapy within his institution and through the Radiation Therapy Oncology Group and the American College of Surgeons Oncology Group. Marcia I. Canto, MD, MHS, is an Assistant Professor of Medicine and Director of Therapeutic Endoscopy and Endoscopic Ultrasonography at The Johns Hopkins Medical Institutions. She completed her gastroenterology-hepatology fellowship and Masters degree program in Clinical Epidemiology at Johns Hopkins University before her Advanced Endoscopy and Endoscopic Research fellowship training at the Case Western Reserve University. She returned to Johns Hopkins to join the faculty in Gastroenterology in 1996. Michael Goggins, MD, is an Assistant Professor of Pathology, Medicine and Oncology at The Johns Hopkins Medical Institutions. Dr. Goggins, a graduate of Trinity College Dublin, trained as a gastroenterologist at St. James Hospital Dublin and at The Johns Hopkins Hospital. He also received training in cancer genetics in The Johns Hopkins University Department of Pathology under the direction of Scott Kern. Since 1999 he has directed the Pancreatic Cancer Early Detection Laboratory. Manuel Hidalgo, MD, PhD, is an Associate Professor of Oncology and codirector of the Drug Development Program at Johns Hopkins University School of Medicine. He received his MD from the University of Navarra Medical School in Pamplona, Spain, and his PhD from the University of Autonoma in Madrid, Spain. In 1997 he began his career as a clinical research fellow at the Cancer Therapy and Research Center in San Antonio, Texas, where he participated in the EORTC/NCI Exchange Fellowship and AACR Young Investigator Fellowship in Clinical Research. He worked as both an Assistant Professor of Medicine at the University of Texas Health Science Center and as a clinical investigator at the Cancer Therapy and Research Center for 2 years before his current position. He obtained an ASCO Career Development Award in 2001. Ralph H. Hruban, MD, received his undergraduate degree at the University of Chicago and his medical degree from Johns Hopkins University School of Medicine. After residency in anatomic pathology at Johns Hopkins, Dr Hruban was a fellow at Memorial Sloan-Kettering Cancer Center. He returned to Johns Hopkins as Chief Resident and joined the faculty in 1990. He is now Professor of Pathology and Oncology, Director of the Division of Gastrointestinal/Liver Pathology, Director of the National Familial Pancreas Tumor Registry, and Deputy Director for Program Development and Faculty, Department of Pathology. His research interests include pancreatic cancer and the precursors to pancreatic cancer. Christine A. Iacobuzio-Donahue, MD, PhD, received her undergraduate degree at Adelphi University and her MD and PhD degrees from Boston University School of Medicine. She completed a residency in anatomic pathology at Johns Hopkins in June 2002, during which she spent a year studying the molecular genetics and gene expression profiles of pancreatic cancer. She is currently a fellow in the Division of Gastrointestinal/Liver Pathology at Johns Hopkins. Her research interests include gene expression profiling of pancreatic cancers and their metastases, as well as drug development studies focused on pancreas cancer. Elizabeth Jaffee, MD, is an Associate Professor of Oncology at The Johns Hopkins University School of Medicine, where she is an internationally recognized leader in the field of cancer vaccine development. Dr Jaffee was among the first to explore vaccination with genetically-modified tumor cells as a way to activate a patient\'s own immune system to fight his/her cancer. Dr Jaffee and her colleagues\' ground-breaking studies in animal models have led to clinical trials for the treatment of patients with renal cell carcinoma, prostate cancer, and pancreatic cancer. Early studies in all of these cancers have already confirmed the promise of this approach and have led to follow-up trials exploring cancer vaccines in patients at high risk for relapse. Dr. Jaffee is particularly well known for the development of human cancer vaccines for patients with pancreatic cancer and for the preclinical studies that were required to design these clinical trials. These studies, published in such prestigious scientific journals as Science, Proceedings of the National Academy of Sciences, Cancer Research, Journal of Clinical Oncology, and the Journal of Immunotherapy have greatly influenced the thinking of scientists around the world, providing a new standard for the design of clinical trials. Scott E. Kern, MD, is a cancer geneticist specializing in research of pancreatic cancer, Smad signaling pathways, and the gene expression patterns of tumor invasion. He attended medical school and completed his residency in pathology at the University of Michigan. Having discovered the joys of genes during his fellowship in the molecular genetics of gastrointestinal cancer at Johns Hopkins, he joined the Johns Hopkins faculty in 1990 to begin his research career. His turn-offs include insincere people and telemarketers. Dan Laheru, MD, is an Instructor in Medical Oncology at The Johns Hopkins University School of Medicine and at the Sidney Kimmel Comprehensive Cancer Center. He received his medical degree from the Baylor College of Medicine in 1995 and completed his residency in internal medicine at the University of Utah. He completed his fellowship in medical oncology at Johns Hopkins in 2000. His most recent awards include the 2000 AACR Bristol Myers Squibb Oncology Fellowship in Clinical Research and the 2000 ASCO Young Investigator Award. Steven D. Leach, MD, is the Paul K. Neumann Professor in Pancreatic Cancer and Chief of the Division of Surgical Oncology at Johns Hopkins University School of Medicine. He is a graduate of Princeton University and the Emory University School of Medicine. After completing his training in General Surgery at Yale, he pursued a fellowship in Surgical Oncology at the University of Texas\NMD Anderson Cancer Center. Dr Leach directs an NIH-funded research program investigating regulation of exocrine differentiation in adult and embryonic pancreas. Anirban Maitra, MD, received his medical degree from the All India Institute of Medical Sciences, after which he completed a residency in anatomic pathology at the University of Texas Southwestern Medical Center in Dallas. He subsequently completed a fellowship in pediatric pathology at the Children\'s Medical Center in Dallas, followed by a fellowship in Gastrointestinal/Liver Pathology at Johns Hopkins. His research interests include familial pancreatic cancer, pediatric gastrointestinal disease, and pediatric neoplasia. Taylor A. Sohn, MD, graduated from The Johns Hopkins University School of Medicine in 1996. She is currently in her seventh year of surgical training, also at Johns Hopkins, pursuing a career in hepatobiliary/pancreatic surgery. She spent 3 years in the molecular genetics laboratory of Dr Scott Kern, studying the genetics of pancreatic cancer. Her other research interests include clinical research related to the care of patients with assorted pancreatic diseases. Robb E. Wilentz, MD, received his undergraduate degree in Biochemical Sciences from Harvard College and his medical degree from Johns Hopkins University School of Medicine. After residency and fellowships in anatomic, surgical, and gastrointestinal pathology at Johns Hopkins, Dr. Wilentz joined the faculty in 2000. He is now Assistant Professor of Pathology in the Division of Gastrointestinal Pathology. His research interests include pancreatic and colorectal cancer, inflammatory bowel disease, and dermatopathology. Charles J. Yeo, MD, is Professor of Surgery and Oncology at the Johns Hopkins University School of Medicine, and an attending surgeon at The Johns Hopkins Hospital. Dr Yeo received his undergraduate degree from Princeton University and his medical degree from The Johns Hopkins University School of Medicine. He trained in General Surgery at The Johns Hopkins Hospital. His primary clinical interests are alimentary tract and hepatopancreatobiliary surgery, and his primary research interests are in pancreatic neoplasia, pancreatic surgery, and intestinal physiology. He has been the Director of the Pancreatic Cancer Interdisciplinary Working Group at Johns Hopkins since 1991. Theresa Pluth Yeo, MSN, MPH, received her undergraduate degree from Cornell University and began her nursing career at The Johns Hopkins Hospital. Ms Yeo completed her MSN and postgraduate adult nurse practitioner program at the University of Virginia. Returning to Johns Hopkins in an internal medicine practice, she received an MPH from the Johns Hopkins University School of Public Health. At the present time, Ms Yeo is an Assistant Professor in the Johns Hopkins University School of Nursing. She is pursuing a doctorate in environmental health science, with emphasis on environmental risk factors related to pancreatic cancer at the Johns Hopkins Bloomberg School of Public Health.

Supported in part by grants from the National Institutes of Health (R01-CA56130 and P50-CA62924).